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Campbell Teskey

Position: 

Professor, Department of Cell Biology & Anatomy

Phone: 
(403) 220-4692
Address: 

Cumming School of Medicine
HSC Room 2103
3300 Hospital Drive NW
Calgary, AB  T2N 4N1

Biography: 

Research Interests:

My research program focuses on three independent but related fields of research that have both basic (curiosity driven) and applied (health sciences) aspects to them: 1) Epilepsy & Seizure Disorders, 2) Stroke Recovery, and 3) The Cellular/Synaptic Basis of Learning & Memory. 

Those of us who wish to study the physical instantiation of memory have traditionally employed experimental phenomena that alter synaptic connectivity in a controlled manner and may utilize the identical, or at least similar, mechanisms to memory formation.  Thus, one of my main lines of research uses two such phenomena: long-term potentiation (LTP) and long-term depression (LTD). 

My work also uses animal models of diseases and syndromes syndromes (vascular insult for stroke and kindling for epilepsy and seizure disorders).  I measure animal behaviour using a variety of assessment techniques (e.g. open field, single pellet reaching task, pasta matrix task, elevated plus maze, cylinder task, ladder task). I also use behavioural experience (skilled-reaching, wheel running, enriched environments) to understand how the brain changes. I employ electrophysiological (EEG, evoked potentials, multi- and single-unit activity), and pharmacological (systemic and focal infusions) techniques to elucidate the underlying mechanisms.

In collaboration with a number of colleagues I have also examined alterations in neural and glial cell anatomy at the cellular, ultrastructural and molecular/genetic levels.  With respect to microscopy, I examine whole cells stained with Golgi, nuclei stained with toluidine blue, and double fluorescent labelling.

Research Activities: 

Understanding how seizures and experience change the brain and behaviour.

Publications: 
Degrees: 
  • Ph.D. (Doctor of Philosophy)