Associate Professor, Schulich School of Engineering, Department of Chemical and Petroleum Engineering
Associate Professor, Cumming School of Medicine, Department of Physiology and Pharmacology
Director, Centre for Bioengineering Research and Education
Calgary Centre for Innovative Technology
Room 122, 2500 University Drive NW
Calgary AB T2N 1N4
Our research focuses on how blood flow affects cell and nanoparticle behavior with relevance to cardiovascular health and disease, stem cells, and cancer. Cells are strongly affected by environmental conditions and adapt by changing their physiology to better suit new environments. One strong environmental factor is fluid flow. Fluid forces resulting from fluid flow can modulate events such as bacterial infection, mammalian cell viability in culture, cancer metastasis, stem cell differentiation, and susceptibility to disease in blood vessels. Understanding the components and mechanisms for cellular response to fluid forces may therefore help us better inhibit infections, more effectively produce bioproducts from mammalian cell culture, and better develop diagnostic and therapeutic technologies. Our work is highly collaborative locally and internationally and has a translational focus around molecular diagnostics, tissue models and devices, drug target identification, and testing of pharmaceuticals, nanoparticles and MRI contrast agents.