Assistant Professor, in the Departments of Physiology & Pharmacology, and Biochemistry & Molecular Biology
Cumming School of Medicine
HRIC Rm 2A08
3280 Hospital Drive NW
Calgary AB T2N 4Z7
Our group studies the epigenetics and epigenomics of brain tumors, with a special emphasis on glioblastoma (GBM). The modest success in treating and curing GBM is at least in part because this cancer is very heterogeneous, and not all tumor cells have the same functional properties. A few cells in these tumors behave like stem cells in a normal tissue, and are responsible for the continuous growth of the malignancy and its recurrence after treatment. We believe that targeting these cancer stem cells will be fundamental in fully eradicating GBM. We have recently discovered that cancer stem cells in GBM have a characteristic way of packaging their DNA. We are currently trying to characterize how cancer stem cells do this, and we are looking for ways to exploit this vulnerability with next generation therapeutics.
Dr. Gallo currently has graduate student and postdoctoral positions available in his research lab.