Professor, Departments of Biochemistry & Molecular Biology, Oncology
3330 Hospital Drive NW
Calgary, AB T2N 4N1
We have found that treatment of many types of cancer cell with oncolytic virus causes apoptosis, but some cancers can acquire resistance. We are seeking to understand this resistance so that strategies to avoid or reverse it may be developed. We are also investigating genomic evolution in cancer and in model bacteria as an indicator of disrupted regulatory pathways.