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Genes & Development

Blood test identifies women at risk of preterm delivery

Researchers in Calgary and Toronto have developed a blood test that detects if a pregnant woman is at risk of delivering her baby prematurely. With an 86 per cent accuracy rate, the new test is more accurate than any existing procedures, according to the lead authors. The study was published July 2016 in PLOS One, a peer-reviewed journal of the Public Library of Science.

Researchers help family find son's genetic cause of autism

Geoffrey Ondrich was diagnosed with autism when he was a child. But like so many cases of the disorder, his parents never understood what caused his condition. Then Dr. Micheil Innes asked the family to participate in a genetic research study.  Through Innes’ research, the Ondrich family found their answer, ending an 18-year search for a cause of their son’s condition.

Research reveals secrets to bacteria in human gut

Amanda Melin, PhD, is studying the bacteria living inside capuchin monkeys to help explain the importance of healthy and diverse bacteria in humans.  Melin is a university alumna, assistant professor in the Faculty of Arts and a member of the Alberta Children’s Hospital Research Institute.

Researcher seeks early clues of damage in kids with congenital heart disease

Dr. Steven Greenway, a paediatric cardiologist and assistant professor in the Cumming School of Medicine, is researching how to help children born with complications from congenital heart disease at the Alberta Children's Hospital.

BPA and its substitute alter brain growth, linked to hyperactivity: study

Deborah Kurrasch, PhD, is the lead researcher in a study published in the Proceedings of the National Academy of Sciences (PNAS) which has provided evidence that BPA and BPS impair the growth of neurons in zebrafish. The findings are so worrying the lead researcher and her colleagues are calling for “removal of all bisphenols from consumer merchandise". 

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Shedding light on pre-eclampsia

University of Calgary researcher Jay Cross, PhD, along with a Stanford University team of investigators, has made an important finding helping to explain what leads to pre-eclampsia. “Our work has cracked open the biggest mystery in preeclampsia, its origins, that have precluded anyone from developing rational treatments,” says Cross, co-principal investigator. The research paper titled, “Endometrial VEGF induces placental sFLT1 and leads to pregnancy complications,” is published in the Journal of Clinical Investigation